Product Profile
Product Name
LTBP1 antibody, C-term
Antibody Type
Primary Antibodies
Product description
More
Rabbit polyclonal to LTBP1 (C-term)The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
Immunogen
KLH conjugated synthetic peptide between 1376~1406 amino acids from the C-terminal region of human LTBP1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
ELISA: Use at 1:1,000:
Species Reactivity
HumanMouse
Concentration
0.2 mg/ml
Target Information
Gene Synonyms
More
Transforming growth factor beta1binding protein1
Latenttransforming growth factor
Latent-transforming growth factor beta-binding protein
isoform 1L
TGFbeta1BP1
Transforming growth factor beta1binding protein 1
LTBP1
LTBP-1
TGF-beta1-BP-1
Transform
Target
LTBP1
Molecular Weight(MW)
173.23 kDa (note)
Application
Application
- Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with LTBP1 antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application
- LTBP1 Antibody (C-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the LTBP1 antibody detected the LTBP1 protein (arrow).
Application Notes
ELISA: Use at 1:1,000:
Additional Information
Form
Liquid
Storage Instructions
Store at at 2-8°C for up to 6 months. For long term storage, aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Storage Buffer
PBS with 0.09% (W/V) sodium azide
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